The San Francisco 49ers have been underdogs three times already this year and have lost twice. Their only win was over the ...

The Rams chase redemption and first place in the NFC West as they face the battered 49ers in a high-stakes Week 10 rematch.

The 49ers have a few decisions to make on potential trade targets ahead of Tuesday's deadline. Who are the best fits for San ...

The San Francisco 49ers entered their Week 9 matchup against the New York Giants as favorites and won. Here were the worst ...

Now that the San Francisco 49ers are at the halfway point of the season, it is a good time to look back on the first nine ...

SANTA CLARA, Calif. – The San Francisco 49ers and PwC proudly announced a new partnership to reshape traditional fan ...

NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Rams ...

NFL.com says teams are calling on Jauan Jennings, but with Aiyuk still ramping up and Shanahan signaling stability, a 49ers ...

Last week, the 49ers barely managed 10 total plays before halftime against the Houston Texans. On Sunday, however, the team ...

The New York Giants play host to the San Francisco 49ers on Sunday in a battle of teams missing multiple star players on both sides of the ball.

Using data from Pro-Football-Reference.com, Stacker compiled a list of the biggest comeback wins in San Francisco 49ers history. Games were ranked according to the largest point deficit by the winning ...