Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect. This metabolic shift is essential for tumor growth, supplying energy, metabolites, and ...
No man is an island, and no neuron is either: complex, intricate connections between and among brain cells are needed for the brain to do its job correctly. Now, researchers from Japan have uncovered ...
Study reveals that reversible chemical modifications can inhibit pyruvate kinase and affect its variants differently, ...
A joint research team from the LKS Faculty of Medicine (HKUMed) and the Faculty of Science at the University of Hong Kong has uncovered an unexpected interaction between chemotherapeutic agents and a ...
Dihydroartemisinin increases a chemical mark called H3K9ac on DNA in liver cells, opening the DNA to turn on the CHAC1 gene. This process is helped by a protein called ATF4, which activates CHAC1 ...
Cells fine-tune gene expression in response to cellular stress, a process critical for tumor progression that leads to cancer. However, elucidating mechanisms governing stress-responsive transcription ...
A joint research team from the LKS Faculty of Medicine (HKUMed) and the Faculty of Science at the University of Hong Kong has uncovered an unexpected interaction between chemotherapeutic agents and a ...