C–C and C–X bond forming reactions are essential tools in organic synthesis, constantly revolutionizing human life. Among the key methods for constructing new chemical bonds are nucleophilic addition ...

In 1887, chemist Sir Arthur Michael reported a nucleophilic addition reaction to the β-position of α,β- unsaturated carbonyl compounds. These reactions, named Michael addition reactions, have been ...

We decided to evaluate the use of alkenes as alkylmetal equivalents in catalytic asymmetric conjugate addition (ACA). These reactions would be strategically important because they would accomplish ...