A new approach targets the B-cell pathway with bispecific antibodies, building on decades of research that establishes the role of B cells and self-reactive antibodies in lupus, systemic sclerosis, ...
An international research group directed by UMC Utrecht has developed and characterized two first-in-class antibodies that specifically block the high-affinity IgG receptor FcγRI. Their findings open ...
The high-affinity Fc gamma receptor I (FcγRI) plays a crucial role in the immune system. Also known as CD64, FcγRI is a high-affinity receptor on myeloid cells that bind to the Fc region of IgG ...
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