Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have ...

Dear Dr. Roach: My doctor put me on Norvasc 10 mg to keep my blood pressure normal. Since Norvasc is a calcium-channel-blocking medicine, can I still take my calcium and vitamin D-3 supplements? I was ...

For adults with type 2 diabetes receiving guideline-directed renin-angiotensin inhibitors (RASi) and sodium-glucose ...

Researchers at the University Medical Center Göttingen (UMG) have shown how a minimal change in a single ion channel increases the sensitivity of sensory cells in the inner ear. Even soft sounds, such ...

Dihydropyridine calcium channel blockers may be linked to worse kidney outcomes for patients with type 2 diabetes, according to study data presented at the European Renal Association Congress in ...

Millions of people around the world take medication every day to control high blood pressure and reduce their risk of heart ...

Ion channels are structures within cell membranes that enable specific ions to travel to and from the cell. Such transfer is essential for a variety of physiological processes such as muscle cell ...

Lysosome malfunction caused by an organelle's inability to clear lipids or other waste from the cell plays a central role in lysosomal storage diseases (LSDs). Though those diseases have disparate ...

Dihydropyridine calcium-channel-blockers (DCCBs), used to treat high blood pressure, could speed up the progression of kidney ...

A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an ...

Sphingolipids are ubiquitous components of membranes and function as bioactive lipid signaling molecules. Here, through genetic screening and lipidomics analyses, we find that the endoplasmic ...