Circulating concentrations of D4A in patients treated with Abi acetate appear to be quite variable. In contrast to hepatic Abi metabolites, it is probable that conversion of Abi to D4A in peripheral ...
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Researcher discovers metabolite of prostate cancer drug more effective at treating aggressive tumors
A metabolite of an FDA-approved drug for metastatic prostate cancer, abiraterone, has more anti-cancer properties than its precursor, researchers have discovered for the first time. Prostate cancer is ...
Metastatic prostate cancer generally responds initially to medical or surgical castration but eventually develops into castration-resistant prostate cancer (CRPC), which is driven by the metabolic ...
Evaluating abiraterone responses in African Americans with metastatic CRPC. This is an ASCO Meeting Abstract from the 2016 Genitourinary Cancers Symposium. This abstract does not include a full text ...
Cleveland Clinic researchers have discovered for the first time that a metabolite of an FDA-approved drug for metastatic prostate cancer, abiraterone (Abi), has more anti-cancer properties than its ...
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