How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Researchers uncovered how cells coordinate genetic compensation when faulty mRNA is degraded. Small RNA fragments act as sequence “addresses” that recruit ILF3 to activate related backup genes.

In today’s rapidly evolving scientific landscape, eliminating barriers to progress is more critical than ever. Precision medicine and targeted therapies hold great promise but are dependent on the ...

AI can help protein engineers optimize the transcription enzymes used to make mRNA-based vaccines and therapeutics, say the authors of a new study.

N of 1 therapy uniquely developed, on demand, for infant with life-threatening rare metabolic disorder in six months Results published in The New England Journal of Medicine and showcased at American ...

Therapeutic mRNA delivered via lipid nanoparticles restored sperm production in genetically infertile mice and produced live ...

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...