Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING ...

Hiroshima University researchers say a newly proposed three-step "detour" pathway for making dolichol, a molecule cells need ...

The transformation of healthy cells into invasive colorectal tumors is an extraordinarily complex process involving numerous molecular mechanisms, according to cancer biologists in China who have ...

Folate coenzymes are pivotal for one-carbon transfers in nucleotide and amino acid metabolism. Microorganisms synthesise folate de novo, making the pathway an attractive target for antimicrobial and ...

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but ...

Enzyme 'atlas' helps researchers decipher cellular pathways Biologists have mapped out more than 300 protein kinases and their targets, which they hope could yield new leads for cancer drugs ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Chloromethane is a gas that is toxic to humans and contributes to the depletion of the ozone layer. It is produced during the ...

NUDT5 enzyme acts as a molecular scaffold that maintains metabolic balance. Inside every cell, a finely tuned metabolic network determines when to build, recycle or stop producing essential molecules.

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a ...

The safety and quality control of parenteral pharmaceuticals, biologics, and medical devices depend heavily on the Bacterial Endotoxin Test (BET). Historically, Limulus Amebocyte Lysate (LAL), derived ...