Researchers devised a reversibly lockable DNA device for enclosing an enzyme and controlling its access to substrates. Turning on and off the activity of a single enzyme on demand is a much desired ...

Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead increase the risk of chronic liver damage and cancer as we age. In a major ...

A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl ...

Epigenetic drug discovery and development programs have attracted much attention and investment in recent years. This is driven by the potential to develop novel therapeutic strategies that can ...