Recently, biology professor Anding Shen landed a $300, 000 grant from the National Institutes of Health (NIH) to study the role of endothelial cells in HIV infection—a project that will occupy her for ...

A study published on Sept. 17 in PLOS Pathogens reports results from a clinical trial of an histone deacetylases (HDAC) inhibitor that had shown potential in preclinical studies and answers open ...

A 36-year-old Brazilian man made headlines around the world in 2020 for being the first person to be putatively cured of human immunodeficiency virus (HIV) using an easily accessible and ...

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, ...

HIV is infamous for its ability to hide in the human body for decades, typically requiring long-term treatment to prevent a rebound from dormancy. In a new study, researchers shed light on where and ...

However, activating NF-kB also has the affect of loosening chromatin, which HIV recruits in another mechanism of latency. Therefore, upregulating the viral activator would be "good for both of these ...

A major bottleneck in curing HIV (human immunodeficiency virus) is that the virus can hide in an inactive form within resting white blood cells, which play a crucial role in coordinating the immune ...

University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly ...

Due to the 4-hour maturation half-life of the Timer protein's blue-to-red chromophore, we can detect reactivated or recently silenced proviruses with high sensitivity using Timer fluorescence.