A schematic diagram illustrates a proposed mechanism of interferon-γ (IFN-γ)-induced downregulation of tricellulin in salivary epithelial cells. IFN-γ leads to the phosphorylation of signal transducer ...

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help ...

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. But it is just as important to resolve that inflammation and return ...

A study published in Immunity reveals that type I interferons (IFN‑I) help resolve inflammation by inducing changes in macrophage mitochondria When our body fights an infection, the immune system must ...

Mount Sinai researchers have identified a cellular mechanism linking infections from influenza A viruses (IAVs) to cardiovascular disease, providing critical insights on how influenza can damage the ...

A recent article in Cell Reports Medicine, by Dr. Felipe Andrade, uncovers insights into lupus symptoms. More specifically, how these symptoms can range in severity among individuals. Andrade is a ...