Researchers from Mount Sinai have uncovered a possible explanation for why a flu infection can lead to heart disease. They’ve shown from work with mouse models and human data how the immune system ...

Researchers elucidated the connection between influenza infection and cardiac disease in mammals by studying human and mouse hearts.

Despite potential benefits, the therapy remains in limited use for myeloproliferative neoplasms (MPNs). Pegylated interferons are a meaningful therapeutic option for the treatment of ...

A new study shows type I interferon fine-tunes macrophage mitochondria through the protein ISG15, boosting dead-cell clearance and limiting inflammatory gene activity.

When a nasty bug infects a cell, the cell sends out riders called interferons that, like Paul Revere, warn the other cells: A virus is coming! A virus is coming! Interferons bind to receptors on the ...

Small-molecule mitochondrial transcription factor A modulators stabilize mtDNA, preventing cytosolic escape and suppressing cGAS-STING interferon signaling, while improving bioenergetics and fibrosis ...