An international team led by National University of Singapore researchers has linked secondary lymphedema to excessive cholesterol buildup inside skin and around lymphatic vessels. Excess cholesterol ...
Please provide your email address to receive an email when new articles are posted on . Gamifant is the first drug approved for adults and children with macrophage activation syndrome in Still’s ...
Visceral fat is the fat stored deep in the abdomen around internal organs. It is strongly linked to inflammation and to higher risk of insulin resistance and type 2 diabetes. Inflammation in fat ...
The white blood cells' typical role is to promote inflammation and stimulate the immune response, but researchers say some actually appear to temper inflammatory conditions and improve healing.
Renal fibrosis originates from diverse etiologies, including diabetes, hypertension, glomerulonephritis and prolonged obstruction, which lead to persistent inflammation and altered repair processes ...
Macrophages serve as the Swiss army knives of the innate immune system, switching between phenotypes to perform different functions in response to the surrounding environment. One of their key ...
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer ...
SPP1+ macrophages identified as key drivers and therapeutic targets in colorectal cancer progression
(A) Volcano plot of DEGs in monocytes/macrophages between NC and CRC samples in the GSE164552 dataset. (B) Venn diagrams of common DEGs up- or down-regulated across the six scRNA-seq datasets (NC vs.
A new study shows type I interferon fine-tunes macrophage mitochondria through the protein ISG15, boosting dead-cell clearance and limiting inflammatory gene activity.
This valuable study presents a technically sophisticated intravital two-photon calcium imaging approach to characterize Ca²⁺ dynamics in distinct populations of meningeal macrophages in awake, freely ...
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