β-Sheet-rich α-synuclein (αS) aggregates characterize Parkinson’s disease (PD). αS was long believed to be a natively unfolded monomer, but recent work suggests it also occurs in α-helix-rich ...
Precise control over the location of monomers in a polymer chain has been described as the ‘Holy Grail’ of polymer synthesis. Controlled chain growth polymerization techniques have brought this goal ...
Generally, in protein and peptide analyses, knowing a molecule’s oligomeric state is useful in determining whether the protein exists in its biologically active form. To this end, the first step ...