NFL Week 18 early picks against spread
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It's Week 18 of the 2025 NFL season and the regular season comes to a close with plenty to play for around the league. The action starts on Saturday with the Carolina Panthers visiting the Tampa Bay Buccaneers with the NFC South on the line and wraps up Sunday night with the Pittsburgh Steelers hosting the Baltimore Ravens for the AFC North title.
We've assembled spread, moneyline and total picks from our Covers Predictions AI tool for every NFL Week 18 game.
Over the course of the season, it has looked at times as if neither the Steelers (9-7) nor the Ravens (8-8) wanted to win the AFC North. The result is a showdown Sunday Night on NBC and Peacock for the division title and the last berth in the playoffs.
The roadmap to Santa Clara will be set this week. USA TODAY Sports provides the early predictions for NFL's pivotal Week 18 slate.
It's a bit tough to just load up on Josh Johnson, but if the Eagles are resting all their starters, it also means their game plan should be pretty vanilla as well, whereas you have to expect a Dan Quinn-coached team to go full pedal to the floor with anyone available in hopes of just finding another win.