Regulation of the actin cytoskeleton by microtubules is mediated by the Rho family GTPases. However, the molecular mechanisms that link microtubule dynamics to Rho GTPases have not, as yet, been ...
A library with single guide RNA (sgRNA) is packed into lentiviral particles and transduced into editor-expressing cells. The sgRNA-transduced cells are selected to generate mutant cells. Mutant cells ...
Nucleotides are essential components of a wide range of cellular processes; therefore, the maintenance of these levels through various metabolic pathways is crucial for adequate cellular function. The ...
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