It has been several months since Dr. Lane Rutledge, who was our colleague in the UAB NF Clinic, passed away unexpectedly, and her absence has been felt by those of us in the NF Clinic as well as by ...

All patients with monofocal OPG seen from January 2004 to January 2011 were included. Best corrected visual acuity (BCVA, LogMAR), contrast sensitivity (Hiding-Heidi low-contrast ‘face’ test (HH) and ...

Nearly 20% of children with NF1 develop pLGGs along the optic pathway, also known as NF1-associated optic pathway glioma (NF1-OPG). Despite many advances in cancer therapy, there are no definitive ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 7 (February 14, 2017), pp. 1702-1707 (6 pages) Although many aspects of optic pathway development are ...

Optic glioma is a brain tumor that grows slowly. Around 75% of diagnoses occur in children younger than 10 years old. Optic glioma accounts for approximately 5% of all childhood brain tumors. The ...

Cavernous malformations of the optic pathway are rare vascular anomalies defined by clusters of dilated, thin‐walled capillaries that may develop along the optic nerve, chiasm, or tract. These lesions ...

Please provide your email address to receive an email when new articles are posted on . PHILADELPHIA — In this video, Michael Fisher, MD, discusses the results of a natural history study he presented ...

Phase 1/2 study of elraglusib (9-ING-41), a small molecule selective glycogen synthase kinase-3 beta (GSK-3β) inhibitor, alone or with irinotecan, temozolomide ...

An award-winning presentation during the 2023 ARRS Annual Meeting explained how the novel technique of three-dimensional (3D) slice-to-volume (SVR) MRI allows for precise delineation and measurement ...

Long-term neurocognitive outcomes in adult survivors of childhood medulloblastoma. Background: The natural history of OPT remains unpredictible and optimal therapeutic management is still ...

The possibility that proteins are modified during axoplasmic transport in central nervous system axons was examined by analyzing neurofilament proteins (200,000, 140,000, and 70,000 mol wt) along the ...