August 24, 2010 — A novel sporadic prion protein disease, variably protease-sensitive prionopathy (VPSPr), with distinct features has been described as the first new prion disease since sporadic ...

Two proteins central to the pathology of Alzheimer's disease act as prions -- misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded ...

New research from Japan suggests that a rare brain-destroying disease caused by rogue prion proteins may be becoming more common—likely due to an aging population. The study, published last month in ...

Kuru A virtually extinct form of human prion disease of the Fore linguistic group of Papua New Guinea transmitted via ritualistic endocannibalism. Mainly affected women and young children. Some ...

We may have been overestimating the role of a pathological class of misfolded protein in neurodegenerative disease. Called prions, these molecules are responsible for conditions such as bovine ...

Prion diseases are a group of different conditions that affect your brain and nervous system. They can cause severe dementia or problems with body control that get worse very quickly. They're rare -- ...

Prion diseases are rare, fatal neurodegenerative disorders caused by misfolded prion proteins (PrP) in the brain. This can lead to memory loss, behavior changes, and movement problems. Prion diseases ...

For many years, the only antemortem clinical laboratory test available for prion disease was limited to the detection of 14-3-3 and total Tau proteins in CSF. As rapid neurodegeneration is a hallmark ...

Close-up on three ropes and marine knots isolated on white background. Each is photographed separately. Prion diseases are rare but deadly neurodegenerative brain diseases that result from misfolding ...

MEDIA AVAILABLE: Images of amyloid beta (A-β) prions revealed by cellular bioassays and headshots of the corresponding authors available here. Media caption and credit information available here. Two ...

"I believe this shows beyond a shadow of a doubt that amyloid beta and tau are both prions, and that Alzheimer's disease is a double-prion disorder in which these two rogue proteins together destroy ...