G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize ...

Scientists discover how yellow fever and encephalitis viruses enter human cells, and block them with decoy molecules.

The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have now discovered ...

(seen here from above) has three parts. If activated, a pore in the receptor opens and allows ions to flow into the cell. PSB-0704 (shown in color) prevents this from happening and blocks, for example ...

Fentanyl is one of the most effective drugs for managing severe pain, yet it carries substantial risks of addiction and ...

Northwestern University scientists have developed the most advanced organoid model for human spinal cord injury to date. In a new study, the research team used lab-grown human spinal cord ...

Understanding the thermodynamic basis of ligand recognition by G-protein-coupled receptors (GPCRs), especially in terms of ...