Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Researchers have identified a molecular brake that limits DNA replication in healthy cells, revealing how cells prevent a long-suspected replication catastrophe and pointing to a potential ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

Abstract Cancer cells precisely modulate replication stress to sustain genomic instability without triggering lethal DNA damage, yet regulators ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...