Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered ...

Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...

Researchers led by Prof. XU Zhiheng from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, revealed the important roles of POSH phase separation and its ...

Liquid-liquid phase separation (LLPS) is a peculiar phenomenon that occurs during crystallization. In a new study, a group of researchers from Doshisha University, Japan, have investigated the ...

Crystallization is a well-explored natural phenomenon where atoms or molecules arrange themselves into highly organized solid forms called crystals. This phenomenon has been widely utilized across ...

The common commensal gut bacterium Bacteroides thetaiotaomicron uses phase separation of the transcription termination factor Rho to colonize and thrive in the mammalian gut, according to a new study ...

Most polymers don’t mix—and that’s the point. Polymer alloys succeed by engineering the interface: use thermodynamics to predict separation, processing to sculpt morphology, and compatibilizers to ...