A research team embarked on a quest to understand the diversity and cellular mechanisms of human Th2 cells. By conducting gene expression analyses of inflamed tissues, they pinpointed a subset of Th2 ...

T cells may be broadly classified as either helper T cells (Th cells, CD4+) or cytotoxic T cells (Tc cells, CD8+). In 1986, T.R. Mosmann, R.L. Coffman, and colleagues observed that individual clones ...

And the most recent article came out of JAMA in 2024, and they found that for every 1 g increase in urinary sodium, you ...

Why do certain immune cells remain permanently active in allergic asthma – even in an environment that should actually damage them? A team from the University Hospital Bonn (UKB) and the University of ...

However, imbalances of IL-6 — too much or too little — can cause disease, even in the absence of infection. Excess IL-6 is central to the pathogenesis of inflammatory reactions like rheumatoid disease ...

Atopic dermatitis (AD) and specific forms of asthma are two medical disorders that are mostly brought on by these inflammations. To fully comprehend the mechanism of therapeutic action and appreciate ...

The gastrointestinal tract is continuously exposed to foreign antigens in food and commensal microbes that have the potential to induce adaptive immune responses for food allergies. Upon genetic ...