RNA interference (RNAi) is a method for targeted gene silencing. It is a highly valuable and widely used technique for the study of gene function and for drug discovery research. During RNAi, ...

The distribution of glycans on a monoclonal antibody impacts its function and half-life. Earlier this month, Masue Marbiah, PhD, a postdoctoral researcher at Imperial College London who develops ...

Titrate siRNAs. Using the lowest possible concentration of siRNA may help avoid unwanted side effects, says Taylor. "Off-target effects can be dose-dependent." Before you start your study, run ...

A fluorescent image of the cell taken four hours into the same experiment. At this time the quantum dot-siRNA complex is distributed throughout the cellular fluid. The dark region in the middle of the ...