Primary biliary cholangitis (PBC) is a rare chronic autoimmune cholangiopathy that mainly affects middle-aged women, ...

Background IBD is characterised by recurrent flares, but evidence on whether modifiable dietary factors influence flare risk ...

Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide. Epidemiological evidence indicates that MASLD is associated with an ...

Background Oncological principles favour en bloc R0 excision for curative endoscopic resection. In Barrett’s neoplasia, ...

Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterised by remarkable cellular ...

Background RNA 5-methylcytosine (m5C) has emerged as a critical epigenetic regulator in cancer biology, yet its role in the tumour immune microenvironment (TME) remains incompletely understood.

Background Both host and microbe metabolism of tryptophan (Trp) is altered in diabetes; however, the molecular mechanisms are ...

Background Depending on the colorectal cancer (CRC) screening programme, a colonoscopy should be performed within 1–3 months after a positive faecal immunochemical test (FIT) result. However, such ...

Mr G S Arul, Department of Paediatric Surgery, Bristol Royal Hospital for Sick Children, St Michael's Hill, Bristol BS2 8BJ, UKsuren{at}sarul.fsnet.co.uk BACKGROUND AND AIMS Mucin genes are expressed ...

1 Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Frontier Science Center of Pathogenic Microorganisms and Infection, School of Basic Medical Sciences, Shanghai Medical College, ...

Functional cure, defined as sustained HBsAg loss with off-treatment viral suppression, is the ultimate goal of antiviral therapy for chronic hepatitis B.1 Yet with current standard-of-care ...

Correspondence to Professor Guy Boeckxstaens, Department of Chronic Diseases, Metabolism, and Ageing, KU Leuven, Leuven, Belgium; guy.boeckxstaens{at}kuleuven.be Objective We evaluated the histamine 1 ...