San Francisco 49ers starting quarterback Brock Purdy won't be active again Sunday vs. the Los Angeles Rams according to a report.

Tom Brady said the San Francisco 49ers should keep Mac Jones starting at quarterback and gives his thoughts on his former teams the New England Patriots and the Tampa Bay Buccaneers.

The Rams vs. 49ers game kicks off at 4:25 p.m. ET/1:25 p.m. PT this Sunday, Nov. 9, 2025. The Week 10 game between the Rams and 49ers will air on FOX. Out-of-market, you can tune in via NFL Sunday Ticket on YouTube TV.

Ferguson, who recorded his first even NFL catch against the 49ers, is the Rams' biggest matchup advantage, especially with Fred Warner not being able to play. However, just because he's good on paper and in flashes, he was drafted for moments like this, so will Ferguson make that massive step needed to put San Francisco on the back foot?

There is no doubting that Brock Purdy is the San Francisco 49ers’ franchise quarterback. But while he continues to recover from a foot injury sustained in the 49ers’ 2025 NFL season

The San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a knee injury.

A prime opportunity is in front of Christian McCaffrey when the San Francisco 49ers play the Los Angeles Rams in Week 10. McCaffrey can become the first player