Here's what we learned from the Rams' 16-point win over the 49ers, which featured four touchdown passes by Matthew Stafford.

The Los Angeles Rams collected a 42-26 win on the road against NFC West rivals San Francisco 49ers on Sunday, but not before a worrisome injury development. In the fourth quarter of the contest, Los Angeles star wide receiver Davante Adams was seen leaving the field with an apparent upper-body injury.

The Los Angeles Rams (7-2) are cooking. Fans and pundits are thinking Super Bowl. Matthew Stafford and the Rams torched the San Francisco 49ers (6-4) on Sunday, 42-26, led by the veteran quarterback's 280 passing yards and four touchdowns.

Matthew Stafford and the Rams pull away in the fourth quarter to defeat the rival San Francisco 49ers 42-26 for their fourth consecutive victory.

The Los Angeles Rams came into Week 10 of the NFL season looking for a little bit of revenge. They went up the California coast to face off against their long-t

Expert recap and game analysis of the Los Angeles Rams vs. San Francisco 49ers NFL game from November 9, 2025 on ESPN.

NFL scores and reports from week 10 of the NFL as the Buffalo Bills are upset by the Miami Dolphins, while the Detroit Lions, Seattle Seahawks and Los Angeles Rams dominate the late games.

WOODLAND HILLS, Ca. The Los Angeles Rams have finalized their roster before their week ten matchup against the San Francisco 49ers. Most of these moves were expected after the team committed to having a new approach in their kicking unit. McVay wanted Jake McQuaide as his long snapper due to his previous work and familiarity.

The 49ers (6-4) fell behind 21-0 early, yielded six touchdowns and produced no takeaways in a 42-26 loss to the Rams (7-2)