Compared to placebo (a sham medication), tirzepatide likely helps adults with obesity lose weight in the medium term (up to 2 years), and this weight reduction is likely to be maintained over the long ...

Liraglutide compared with placebo (a sham medication) likely increases the number of people who lose at least 5% of their body weight, but its impact on unwanted effects, quality of life, and major ...

Adults with obesity lose more weight with semaglutide than with placebo (a sham medication). However, the risk of unwanted events is probably higher than with placebo after 24 months. Semaglutide ...

In people with cancer, CBT-I may slightly improve insomnia severity, sleep quality, and most sleep diary parameters without introducing additional unwanted or harmful events. However, we are very ...

Side effects of acupuncture include dizziness, nausea, bruising, insomnia, abdominal pain, and skin rashes, which should be considered when weighing potential benefits and risks.

Molnupiravir is a pill used to treat COVID-19 in people who are at high risk of developing severe illness. It works by interfering with the ability of SARS‑CoV‑2 (the virus that causes COVID-19) to ...

• Antibiotics seem to reduce surgical site infections in people undergoing surgery to fix the lower limb arteries (peripheral arterial reconstruction of the lower limb).

Sedation using propofol instead of traditional sedatives may improve recovery time and patient satisfaction scores for people undergoing colonoscopy. Propofol sedation has little to no effect on ...

The first module on intro to systematic review gave me clear and comprehensive knowledge on why this research method is important to all key holders and why there is a need for more people (both ...

Through our global network of Cochrane Groups, we harness a wide variety of specialist interests, skills and knowledge that help us create high quality, relevant health evidence. Our Thematic Groups ...

If you are a patient, their family or carer, you can play a vital role in our work. Health professionals, translators, researchers and the public can all make a difference to global health. When you ...

Nous examinons les données probantes qui sous-tendent les questions affectant la vie des gens, leur donnant les moyens de prendre de meilleures décisions. Nous produisons des données probantes ...