A prime opportunity is in front of Christian McCaffrey when the San Francisco 49ers play the Los Angeles Rams in Week 10.

An incident involving San Francisco 49ers star running back Christian McCaffrey led to a punishment from the NFL this weekend ...

The NFL Officiating Department reviewed the incident, and they have now made their final decision. The league announced on ...

Olivia Culpo is getting real about what life looks like now that she’s married to San Francisco 49ers star Christian ...

McCaffrey was involved in an incident in the fourth quarter that resulted in a 15-yard penalty. Giants defensive back Dane ...

San Francisco 49ers running back Christian McCaffrey is on pace for another historic season, potentially etching his name ...

The 29-year-old McCaffrey also hit another NFL milestone.

Christian McCaffrey has fully rebounded from an earlier-season injury, and that's bad news for the Los Angeles Rams.

McCaffrey ran for a three-yard score to put the 49ers up on the Giants 34-17 with 4:13 left to play and that gave him 16 ...

Christian McCaffrey made history in San Francisco's Sunday win at the New York Giants as he set a new NFL record.

The Week 10 NFL schedule kicks with the Denver Broncos vs. the Las Vegas Raiders in an AFC West showdown on 'Thursday Night ...

The 49ers have played over their head in their 6-3 start, which could have made them a candidate for upgrades at Tuesday's ...