49ers, Los Angeles Rams and San Francisco
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Christian McCaffrey #23 of the San Francisco 49ers runs with the ball during the game against the Los Angeles Rams at Levi’s Stadium on November 9, 2025 in Santa Clara, California. Matthew Stafford #9 of the Los Angeles Rams throws during the game against the San Francisco 49ers at Levi’s Stadium on November 9, 2025 in Santa Clara, California.
Los Angeles Rams quarterback Matthew Stafford had another outstanding day on Sunday as his squad downed the San Francisco 49ers 42-26, but one play stood out more than the rest.
The way Matthew Stafford and the Los Angeles Rams picked apart the injury-riddled defense for San Francisco, it raised questions about why the 49ers weren’t more aggressive before last week’s trade deadline.
Matthew Stafford and the Rams pull away in the fourth quarter to defeat the rival San Francisco 49ers 42-26 for their fourth consecutive victory.
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49ers starting LB suffers first-quarter injury vs. Rams in Week 10
The San Francisco 49ers have already lost Fred Warner for the year, and now they may have to play without his replacement.
Los Angeles wide receiver Davante Adams has an oblique injury that led to his exit in the fourth quarter of the 42-26 win over the host San Francisco 49ers on Sunday, Rams coach Sean McVay said after the game.
Matthew Stafford passes for 280 yards and four touchdowns as the Rams defeat the 49ers 42-26 to set up an NFC West showdown with the Seattle Seahawks next week.
San Francisco 49ers head coach Kyle Shanahan announced the team's starting quarterback for Week 10's matchup against the Rams.
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