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  1. NARCAN® Nasal Spray

    Naloxone, the active ingredient in NARCAN® Nasal Spray, competes with opioids to bind with the same receptors in the brain, reversing the effects of an opioid overdose in 2 to 3 minutes.

  2. Naloxone - Wikipedia

    Naloxone, sold under the brand name Narcan among others, is an opioid antagonist, a medication used to reverse or reduce the effects of opioids. [14] For example, it is used to restore …

  3. Narcan Nasal Spray: Opioid Overdose, Instructions and more

    Jul 11, 2024 · Narcan nasal spray (naloxone) is an over-the-counter medicine used to treat an opioid overdose emergency, Narcan works by rapidly reversing the opioid's effects.

  4. Narcan: Dosage, How It's Given, How It Works, Uses, and More

    Sep 28, 2023 · Narcan is used for emergency treatment of opioid overdose. It’s an opioid antagonist, which means it works by blocking certain receptors (attachment sites) in your body …

  5. 5 Things to Know About Naloxone | Overdose Prevention | CDC

    May 2, 2024 · Naloxone, for example Narcan®, is a medicine that can help people who are overdosing on an opioid. Opioids include prescription medications, heroin, and fentanyl.

  6. Naloxone DrugFacts | National Institute on Drug Abuse (NIDA)

    Jan 11, 2022 · Prepackaged Nasal Spray (generic naloxone, Narcan®, Kloxxado®), developed as a result of NIDA-funded research, is an FDA-approved prefilled, needle-free device that …

  7. How Narcan works: Mechanism of action explained

    Jul 3, 2025 · Narcan (naloxone) is an over-the-counter (OTC) medication that treats opioid overdose. Its mechanism of action is to quickly block opioids in your system.

  8. Naloxone (Narcan) Nasal Spray - WebMD

    Sep 11, 2024 · Naloxone – also known as Narcan – is a medication that can reverse the effects of an opioid overdose. This includes heroin, fentanyl, and some types of painkillers.

  9. What is Narcan (naloxone)? Uses, how it works, and where to ...

    May 30, 2025 · Learn what Narcan (naloxone) is, how it reverses opioid overdoses, where to get it, and how to use it safely with support from QuickMD

  10. Wait and watch the person closely. If the person does not respond in 2-mins, repeat the steps and give the second dose of Narcan® Nasal Spray in box. Call 911 right away, if you have not …